Concepedia

Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans

Adam D. Shilling, Frank M. Nedza, Thomas Emm, Sharon Diamond, Edward McKeever, Naresh Punwani, William V. Williams, Argyrios G. Arvanitis, Laurine G. Galya, Mei Li,

Drug Metabolism and Disposition · 2010 · 111 citations · 9 references

DOI

Concepts

References

9

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

, , +16

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

Evan Parganas, Demin Wang, Dimitrios J. Stravopodis et al. · Cell · 1998 · 1.2K citations · Full text

, , +11

Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis

Hans Neubauer, Ana Cumano, Mathias Müller et al. · Cell · 1998 · 915 citations · Full text

, , +10

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

Alfonso Quintás‐Cardama, Kris Vaddi, Phillip Liu et al. · Blood · 2010 · 827 citations

, , +11

Determination of mean valproic acid serum level by assay of a single pooled sample

Robert A. Hamilton, William R. Garnett, Berry J. Kline · Clinical Pharmacology & Therapeutics · 1981 · 256 citations

, , +15