Concepedia

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

Janeen H. Trembley, Gretchen M. Unger, Vicci L. Korman, Diane Tobolt, Zygmunt Kazimierczuk, Lorenzo A. Pinna, Betsy T. Kren, Khalil Ahmed

Cancer Letters · 2011 · 40 citations · 39 references

DOI

Concepts

References

39

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

, , +12

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

Ji Luo, Nicole L. Solimini, Stephen J. Elledge · Cell · 2009 · 1.8K citations · Full text

, , +14

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

Justin P. Dassie, Xiuying Liu, Gregory S. Thomas et al. · Nature Biotechnology · 2009 · 585 citations · Full text

, , +13

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

Adam Siddiqui-Jain, Denis Drygin, Nicole Streiner et al. · Cancer Research · 2010 · 513 citations

, , +16

REACTIVE STROMA IN PROSTATE CANCER PROGRESSION

Jennifer A. Tuxhorn, Gustavo E. Ayala, David R. Rowley · The Journal of Urology · 2001 · 496 citations

, , +6