Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments

William Lehman, Victoria Hatch, Vicci L. Korman, +7

Journal of Molecular Biology

Natural SciencesActin IsoformsMolecular BiologyCell MotilityCytoskeleton +7

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

Betsy T. Kren, Gretchen M. Unger, Lucas Sjeklocha, +5

Journal of Clinical Investigation

Endothelial CellsHyaluronan NanocapsulesImmunologyBiomedical EngineeringNanocapsule-delivered Sleeping Beauty +21

CK2 Modulation of NF-κB, TP53, and the Malignant Phenotype in Head and Neck Cancer by Anti-CK2 Oligonucleotides <i>In vitro</i> or <i>In vivo</i> via Sub–50-nm Nanocapsules

Matthew S. Brown, Oumou Diallo, Michael Y. Hu, +9

Clinical Cancer Research

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice

Janeen H. Trembley, Gretchen M. Unger, Diane Tobolt, +6

Molecular and Cellular Biochemistry

UrologySystemic AdministrationCancer Cell BiologyXenograft Prostate TumorsAntisense Oligonucleotides +6

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

Janeen H. Trembley, Gretchen M. Unger, Vicci L. Korman, +5

Cancer Letters

NanomedicineTargets Malignant CancerDrug TargetingSmall MoleculesNano-drug Delivery +7

Structural Dynamics of the Actin–Myosin Interface by Site-directed Spectroscopy

Vicci L. Korman, Sarah E. Anderson, Ewa Próchniewicz, +2

Journal of Molecular Biology

Single Molecule BiophysicsNatural SciencesMolecular BiologyActin–myosin InterfaceCell Motility +4

Mechanism and Efficacy of Sub–50-nm Tenfibgen Nanocapsules for Cancer Cell–Directed Delivery of Anti-CK2 RNAi to Primary and Metastatic Squamous Cell Carcinoma

Gretchen M. Unger, Betsy T. Kren, Vicci L. Korman, +5

Molecular Cancer Therapeutics

NanoparticlesNanotherapeuticsEngineeringBiomedical EngineeringTumor Biology +21

Mutations in Actin Subdomain 3 That Impair Thin Filament Regulation by Troponin and Tropomyosin

Vicci L. Korman, Larry S. Tobacman

Journal of Biological Chemistry

Molecular BiologyCytoskeletonHybrid Thin FilamentsCellular PhysiologyThin Filament +16

An Actin Subdomain 2 Mutation That Impairs Thin Filament Regulation by Troponin and Tropomyosin

Vicci L. Korman, Victoria Hatch, Kavara Y. Dixon, +3

Journal of Biological Chemistry

Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice

Janeen H. Trembley, Gretchen M. Unger, Vicci L. Korman, +6

PLoS ONE

NanomedicineChimeric OligomerEngineeringDrug TargetingS50-tbg Nanoencapsulation Technology +11