Genesegues (United States)

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

Betsy T. Kren, Gretchen M. Unger, Lucas Sjeklocha et al. · Journal of Clinical Investigation · 2009 · 105 citations · Full text

Pharmacy, Bioengineering, Biotechnology +17

CK2 Modulation of NF-κB, TP53, and the Malignant Phenotype in Head and Neck Cancer by Anti-CK2 Oligonucleotides <i>In vitro</i> or <i>In vivo</i> via Sub–50-nm Nanocapsules

Matthew S. Brown, Oumou Diallo, Michael Y. Hu et al. · Clinical Cancer Research · 2010 · 84 citations · Full text

Medicine, Molecular Biology, Oncology +16

Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

Betsy T. Kren, Gretchen M. Unger, Md. Joynal Abedin et al. · Breast Cancer Research · 2015 · 70 citations · Full text

Medicine, Cancer Biology, Oncology +16

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

Janeen H. Trembley, Gretchen M. Unger, Vicci L. Korman et al. · Cancer Letters · 2011 · 40 citations

Pharmacy, Oncology, Pharmacology +16

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α′ subunits reduces orthotopic xenograft prostate tumors in mice

Janeen H. Trembley, Gretchen M. Unger, Diane Tobolt et al. · Molecular and Cellular Biochemistry · 2011 · 40 citations

Medicine, Molecular Biology, Oncology +9