The residual risk of sepsis: modeling the effect of concentration on bacterial detection in two‐bottle culture systems and an estimation of false‐negative culture rates

Abstract

Continuing reports of septic reactions after transfusion of culture-tested apheresis PLTs, and frequent single-bottle-positive results when testing with two-bottle systems, suggest appreciable levels of false-negative results with a commercially available bacterial detection system (BacT/ALERT, bioMéreiux) as implemented.