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Spiro-naphthyridinone piperidines as inhibitors of S. aureus and E. coli enoyl-ACP reductase (FabI)

Peter B. Sampson, Christine J. Picard, Sean Handerson, T.E. McGrath, Domagala Megan, Andrew Leeson, V. Romanov, Donald E. Awrey, D. Thambipillai, Elias Bardouniotis,

Bioorganic & Medicinal Chemistry Letters · 2009 · 23 citations · 6 references

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6

Abstract of papers

Antonius W.T. Konings, H. Joenje, Aalt Bast et al. · Pharmacy World & Science · 1987 · 428 citations

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

Sophie Brinster, Gilles Lamberet, Bart Staels et al. · Nature · 2009 · 324 citations

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Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Mark A. Seefeld, William H. Miller, Kenneth A. Newlander et al. · Journal of Medicinal Chemistry · 2003 · 161 citations · Full text

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Dirk A. Heerding, George Chan, Walter E. DeWolf et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 124 citations · Full text

, , +12

Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

William H. Miller, Mark A. Seefeld, Kenneth A. Newlander et al. · Journal of Medicinal Chemistry · 2002 · 110 citations · Full text

, , +16