Amyloid Precursor Protein Enhances Nav1.6 Sodium Channel Cell Surface Expression

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg, Mats Gullberg, Malin Jarvius et al. · Nature Methods · 2006 · 2.4K citations

Protein Chemistry, Protein Function, Proximity Ligation +8

High-Level Neuronal Expression of Aβ_1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +15

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

Laure Verret, Edward O. Mann, Giao B. Hang et al. · Cell · 2012 · 1.2K citations · Full text

Alzheimer Model, Neuropsychology, Alzheimer's Disease +11

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

Marc Aurel Busche, Gerhard Eichhoff, Helmuth Adelsberger et al. · Science · 2008 · 1.1K citations

Synaptic Transmission, Neurochemical Biomarkers, Neurotransmission +18

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

Claudio A.P. Joazeiro, Simon S. Wing, Han-kuei Huang et al. · Science · 1999 · 1K citations

Protein Function, Signal Transduction, Signaling Pathway +13