An Indigenous Posttranscriptional Modification in the Ribosomal Peptidyl Transferase Center Confers Resistance to an Array of Protein Synthesis Inhibitors

Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

Tomoya Baba, Takeshi Ara, Miki Hasegawa et al. · Molecular Systems Biology · 2006 · 8.2K citations · Full text

Life Sciences, Genetics, Microbiology +9

The Comparative RNA Web (CRW) Site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs

Jamie J. Cannone, Sankar Subramanian, Murray N. Schnare et al. · BMC Bioinformatics · 2002 · 1.6K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

Frank Schlünzen, Raz Zarivach, J. Harms et al. · Nature · 2001 · 1.1K citations

Life Sciences, Biochemistry, Microbiology +11

Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit

J.L. Hansen, Peter B. Moore, Thomas A. Steitz · Journal of Molecular Biology · 2003 · 392 citations

Life Sciences, Biochemistry, Molecular Biology +15

Loss of a conserved 7‐methylguanosine modification in 16S rRNA confers low‐level streptomycin resistance in bacteria

Susumu Okamoto, Aki Tamaru, Chie Nakajima et al. · Molecular Microbiology · 2007 · 299 citations

Life Sciences, Microbiology, Molecular Biology +13