Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance

Banting Lecture 2001

Julie McGarry · Diabetes · 2002 · 1.4K citations · Full text

Metabolic Disorder, Censorship, Obesity +17

Disordered Fat Storage and Mobilization in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

Gary F. Lewis, André C. Carpentier, Khosrow Adeli et al. · Endocrine Reviews · 2002 · 1.3K citations · Full text

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

M.Dodson Michael, Rohit Kulkarni, Catherine Postic et al. · Molecular Cell · 2000 · 1.2K citations · Full text

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +15

A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

Jens C. Brüning, M.Dodson Michael, Jonathon N. Winnay et al. · Molecular Cell · 1998 · 1.2K citations · Full text

Obesity, Metabolic Syndrome, Insulin Resistance +11

Fat Accumulation in the Liver Is Associated with Defects in Insulin Suppression of Glucose Production and Serum Free Fatty Acids Independent of Obesity in Normal Men

Anneli Seppälä‐Lindroos, Satu Vehkavaara, Anna‐Maija Häkkinen et al. · The Journal of Clinical Endocrinology & Metabolism · 2002 · 1.1K citations