FGF21 gene therapy as treatment for obesity and insulin resistance

Verónica Jiménez, Claudia Jambrina, Estefanía Casana, +21

EMBO Molecular Medicine

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance

Ivet Elias, Sylvie Franckhauser, Tura Ferré, +9

Diabetes

Metabolic DisorderImmunologyInsulin SignalingOxidative StressObesity +17

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver

Tura Ferré, Efrén Riu, Fátima Bosch, +1

The FASEB Journal

Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice

Sylvie Franckhauser, Ivet Elias, Victoria Rotter Sopasakis, +7

Diabetologia

InflammationMetabolic SyndromeCytokineLiver PhysiologyPhysiology +10

Correction of diabetic alterations by glucokinase.

Tura Ferré, Anna Pujol, Efrén Riu, +2

Proceedings of the National Academy of Sciences

Metabolic SyndromeKetone BodyDiabetes ManagementBiochemistryDiabetes +13

Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance

Tura Ferré, Efrén Riu, Sylvie Franckhauser, +2

Diabetologia

Insulin ResistanceMetabolic SyndromeHepatologyLiver PhysiologyDiabetes +10

Adipose Overexpression of Phospho<i>enol</i>pyruvate Carboxykinase Leads to High Susceptibility to Diet-Induced Insulin Resistance and Obesity

Sylvie Franckhauser, Sergio Muñoz, Ivet Elias, +2

Diabetes

Metabolic DisorderTransgenic MiceAdipose OverexpressionInsulin SignalingObesity +17

In Vivo Adeno-Associated Viral Vector–Mediated Genetic Engineering of White and Brown Adipose Tissue in Adult Mice

Verónica Jiménez, Sergio Muñoz, Estefanía Casana, +7

Diabetes

Metabolic RemodelingInsulin SignalingObesityMetabolic SyndromeCell Signaling +18

Acute activation of central GLP-1 receptors enhances hepatic insulin action and insulin secretion in high-fat-fed, insulin resistant mice

Melissa A. Burmeister, Tura Ferré, Jennifer Ayala, +3

American Journal of Physiology-Endocrinology and Metabolism

Glucose ToleranceCentral Glp-1 ReceptorsInsulin SignalingGastrointestinal Peptide HormoneObesity +17

Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy

David Callejas, Christopher J. Mann, Eduard Ayuso, +15

Diabetes

ImmunologyLong-term SurvivalInsulin SignalingMetabolic SyndromeTranslational Medicine +15