Inhibition of lysine-specific demethylase 1 by the acyclic diterpenoid geranylgeranoic acid and its derivatives

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

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Life Sciences, Genetics, Molecular Biology +11

Prevention of Second Primary Tumors by an Acyclic Retinoid, Polyprenoic Acid, in Patients with Hepatocellular Carcinoma

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Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

Johannes H. Schulte, Soyoung Lim, Alexander Schramm et al. · Cancer Research · 2009 · 442 citations

Medicine, Cancer Biology, Oncology +16

<i>trans</i>-2-Phenylcyclopropylamine Is a Mechanism-Based Inactivator of the Histone Demethylase LSD1

Dawn M. Z. Schmidt, Dewey G. McCafferty · Biochemistry · 2007 · 303 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Claudia Binda, Sérgio Valente, Mauro Romanenghi et al. · Journal of the American Chemical Society · 2010 · 285 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16