Dewey G. McCafferty

Histone H3 Lysine 4 Demethylation Is a Target of Nonselective Antidepressive Medications

Min Gyu Lee, Christopher Wynder, Dawn M. Z. Schmidt et al. · Chemistry & Biology · 2006 · 441 citations

Life Sciences, Molecular Biology, Pharmacology +14

<i>trans</i>-2-Phenylcyclopropylamine Is a Mechanism-Based Inactivator of the Histone Demethylase LSD1

Dawn M. Z. Schmidt, Dewey G. McCafferty · Biochemistry · 2007 · 303 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Vinyl Sulfones:  Inhibitors of SrtA, a Transpeptidase Required for Cell Wall Protein Anchoring and Virulence in <i>Staphylococcus aureus</i>

Brenda A. Frankel, Matthew L. Bentley, Ryan G. Kruger et al. · Journal of the American Chemical Society · 2004 · 206 citations

Life Sciences, Medicinal Chemistry, Microbiology +17

Analysis of the Substrate Specificity of the <i>Staphylococcus aureus</i> Sortase Transpeptidase SrtA

Ryan G. Kruger, Balint Otvos, Brenda A. Frankel et al. · Biochemistry · 2004 · 140 citations

Life Sciences, Microbiology, Molecular Biology +17

<i>Staphylococcus aureus</i> Sortase Transpeptidase SrtA:  Insight into the Kinetic Mechanism and Evidence for a Reverse Protonation Catalytic Mechanism

Brenda A. Frankel, Ryan G. Kruger, Dana Robinson et al. · Biochemistry · 2005 · 139 citations

Life Sciences, Biochemistry, Molecular Biology +17