Dawn M. Z. Schmidt

Histone H3 Lysine 4 Demethylation Is a Target of Nonselective Antidepressive Medications

Min Gyu Lee, Christopher Wynder, Dawn M. Z. Schmidt et al. · Chemistry & Biology · 2006 · 441 citations

Life Sciences, Molecular Biology, Pharmacology +14

<i>trans</i>-2-Phenylcyclopropylamine Is a Mechanism-Based Inactivator of the Histone Demethylase LSD1

Dawn M. Z. Schmidt, Dewey G. McCafferty · Biochemistry · 2007 · 303 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Evolutionary Potential of (β/α)₈-Barrels:  Functional Promiscuity Produced by Single Substitutions in the Enolase Superfamily

Dawn M. Z. Schmidt, Emily C. Mundorff, Michael Dojka et al. · Biochemistry · 2003 · 171 citations

Life Sciences, Biochemistry, Evolutionary Biology +17

Evolution of Enzymatic Activities in the Enolase Superfamily:  Functional Assignment of Unknown Proteins in <i>Bacillus subtilis </i>and <i>Escherichia coli</i> as <scp>l</scp>-Ala-<scp>d</scp>/<scp>l</scp>-Glu Epimerases

Dawn M. Z. Schmidt, Brian K. Hubbard, J.A. Gerlt · Biochemistry · 2001 · 84 citations

Life Sciences, Biochemistry, Microbiology +15

Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B

David M. Gooden, Dawn M. Z. Schmidt, Julie A. Pollock et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 75 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15