p53 promotes cellular survival in a context-dependent manner by directly inducing the expression of haeme-oxygenase-1

Haem oxygenase-1 prevents cell death by regulating cellular iron

Christopher D. Ferris, Samie R. Jaffrey, Akira Sawa et al. · Nature Cell Biology · 1999 · 511 citations

Life Sciences, Biochemistry, Cell Biology +14

Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine

Wynand P. Roos, Luís F.Z. Batista, Steffen C. Naumann et al. · Oncogene · 2006 · 497 citations

Medicine, Oncology, Pharmacology +14

p53 regulates maternal reproduction through LIF

Wenwei Hu, Zhaohui Feng, Angelika K. Teresky et al. · Nature · 2007 · 454 citations

Life Sciences, Genetics, Molecular Biology +9

Identification and classification of p53-regulated genes

Jian Yu, Lin Zhang, Paul M. Hwang et al. · Proceedings of the National Academy of Sciences · 1999 · 453 citations

Medicine, Cell Biology, Oncology +13

Distinct Roles for JNK1 and JNK2 in Regulating JNK Activity and c-Jun-Dependent Cell Proliferation

Kanaga Sabapathy, Konrad Hochedlinger, Shin Yuen Nam et al. · Molecular Cell · 2004 · 393 citations · Full text

Life Sciences, Biochemistry, Cell Biology +9