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Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome

Protein ChemistryMedicinal ChemistryP3 Threonine ResidueBiochemistryNatural SciencesMedicineProteomicsPeptide LibraryProteasomeChymotrypsin-like ActivityPeptide SynthesisHuman 20SChemical BiologyPharmacologyDrug Discovery