Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes.

Joseph C. Kolars, Phyllissa Schmiedlin‐Ren, John D. Schuetz et al. · Journal of Clinical Investigation · 1992 · 533 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Paul B. Watkins, Steven Wrighton, Erin G. Schuetz et al. · Journal of Clinical Investigation · 1987 · 483 citations · Full text

Medicine, Biochemistry, Molecular Biology +13

First-pass metabolism of cyclosporin by the gut

Joseph C. Kolars, Paul B. Watkins, Robert M. Merion et al. · The Lancet · 1991 · 428 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole

Klaus T. Olkkola, Janne T. Backman, Pertti J. Neuvonen · Clinical Pharmacology & Therapeutics · 1994 · 412 citations

Medicine, Pharmacokinetics, Pharmacology +14

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily

Jack Gorski, Stephen D. Hall, D. I. Jones et al. · Biochemical Pharmacology · 1994 · 397 citations

Medicine, Medicinal Chemistry, Pharmacology +12