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Virtual cofactors for an Escherichia coli nitroreductase enzyme: Relevance to reductively activated prodrugs in antibody directed enzyme prodrug therapy (ADEPT)

EngineeringBiochemistryNatural SciencesEnzyme CatalysisBioconjugationBiotechnologySynthetic BiologyEnzyme Prodrug TherapyAntibody EngineeringProtein EngineeringMicrobiologyStructure-function Enzyme KineticsActivated ProdrugsVirtual Cofactors