Transforming growth factor-β inhibits cystogenesis in human autosomal dominant polycystic kidney epithelial cells

TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes

Lynn Sanford, Ilona Ormsby, Adriana C. Gittenberger–de Groot et al. · Development · 1997 · 1.4K citations · Full text

Tgfbeta2 Gene, Brain Development, Immunology +18

Identification of multiple active growth factors in basement membrane matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components

Slobodan Vukičević, Hynda K. Kleinman, Frank P. Luyten et al. · Experimental Cell Research · 1992 · 688 citations

Cellular Activity, Medicine, Cell-matrix Interaction +9

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

Kohei Miyazono, Ulf Hellman, Christer Wernstedt et al. · Journal of Biological Chemistry · 1988 · 642 citations · Full text

Structural Characterization, Human Growth, Human Platelets +23

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

Klaus Piontek, Luís F. Menezes, Miguel A. García-González et al. · Nature Medicine · 2007 · 414 citations

Urology, Developmental Biology, Cell Division +11

cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway

Tamio Yamaguchi, Jill C. Pelling, Nadja T. Ramaswamy et al. · Kidney International · 2000 · 348 citations · Full text

Cell Physiology, Urology, Signal Transduction +10