Kidney tubule remodeling is the academic concept and research field focused on the dynamic structural and functional alterations occurring within the renal tubules. This encompasses the study of cellular plasticity, morphological changes (such as epithelial dedifferentiation, proliferation, and re-differentiation), and the underlying molecular and cellular mechanisms driving adaptive or maladaptive responses to injury, disease, or physiological stress, including processes of regeneration, repair, and fibrosis.