Concepedia

Regulation of arachidonate metabolism via lipoxygenase and cyclo-oxygenase by 12-HPETE, the product of human platelet lipoxygenase

Marvín I. Siegel, Randy T. McConnell, Sanders L. Abrahams, Ned A. Porter, Pedro Cuatrecasas

Biochemical and Biophysical Research Communications · 1979 · 206 citations · 19 references

DOI

Concepts

References

19

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

, , +10

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

J. Bryan Smith, A.L. Willis · Nature New Biology · 1971 · 1.5K citations

, , +14

Arachidonate lipoxygenase in blood platelets

D.H. Nugteren · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1975 · 619 citations

, , +14

A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, Stuart Bunting et al. · Prostaglandins · 1976 · 605 citations

, , +16

Mechanism for irreversible self-deactivation of prostaglandin synthetase.

Robert W. Egan, James W. Paxton, F. A. Kuehl · Journal of Biological Chemistry · 1976 · 589 citations · Full text

, , +9