Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

Philip W. Kantoff, Celestia S. Higano, Neal D. Shore et al. · New England Journal of Medicine · 2010 · 5.5K citations · Full text

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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Pingyan Cheng, Cesar A. Corzo, Noreen Luetteke et al. · The Journal of Experimental Medicine · 2008 · 895 citations · Full text

Life Sciences, Immunology, Oncology +17

Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.

Jan Schmielau, Olivera J. Finn · PubMed · 2001 · 872 citations

Life Sciences, Immunology, Oncology +11

Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients

Jennifer S. Ko, Arnold H. Zea, Brian I. Rini et al. · Clinical Cancer Research · 2009 · 852 citations

Medicine, Oncology, Pharmacology +17

A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells

Bastian Hoechst, Lars A. Ormandy, Matthias Ballmaier et al. · Gastroenterology · 2008 · 782 citations · Full text

Medicine, Immunology, Oncology +14