Jan Schmielau

Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients.

Jan Schmielau, Olivera J. Finn · PubMed · 2001 · 872 citations

T-regulatory Cell, Immunology, Blood Cell +18

Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.

Wolff Schmiegel, Christian Roeder, Jan Schmielau et al. · Proceedings of the National Academy of Sciences · 1993 · 104 citations · Full text

Tgf-alpha Protein, Signal Transduction, Signaling Pathway +15

Suppressed T-cell receptor zeta chain expression and cytokine production in pancreatic cancer patients.

Jan Schmielau, Michael A. Nalesnik, Olivera J. Finn · PubMed · 2001 · 62 citations

T-regulatory Cell, Immunology, Immune Regulation +20

Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution

Nehad M. Alajez, Jan Schmielau, Mark D. Alter et al. · Blood · 2005 · 43 citations · Full text

Cytokine-mediated enhancement of epidermal growth factor receptor expression provides an immunological approach to the therapy of pancreatic cancer

Wolff Schmiegel, Jan Schmielau, Doris Henne‐Bruns et al. · Proceedings of the National Academy of Sciences · 1997 · 28 citations · Full text

Tumor Necrosis Factor, Cancer Immunosurveillance, Pancreatic Cancer +14