Enzymatic synthesis of peptidyl amino alcohols and peptidyl amino aldehydes-serine proteinase inhibitors

Inhibition of the proteolytic activity of the multicatalytic proteinase complex (proteasome) by substrate-related peptidyl aldehydes.

Alexander Vinitsky, Christopher Cardozo, Laura Sepp‐Lorenzino et al. · Journal of Biological Chemistry · 1994 · 112 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

New methods and reagents in organic synthesis, 29, A practical method for the preparation of optically acive N-protected .ALPHA.-amino aldehydes and peptide aldehydes.

Yasumasa Hamada, Takayuki Shioiri · Chemical and Pharmaceutical Bulletin · 1982 · 111 citations · Full text

Natural Sciences, Chemistry, Organic Chemistry +7

Studies on Optically Active Amino Acids. V. Synthesis of Optically Active α-Aminoalcohols by the Reduction of α-Amino Acid Esters with Sodium Borohydride

Hedeo Seki, Kenji Koga, Hisayuki Matsuo et al. · Chemical and Pharmaceutical Bulletin · 1965 · 82 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +8

Emerimicins III and IV and their ethylalanine12 epimers. Facilitated chemical-enzymatic synthesis and a qualitative evaluation of their solution structures

Urszula Słomczyńska, Denise D. Beusen, Janusz Zabrocki et al. · Journal of the American Chemical Society · 1992 · 47 citations

Natural Sciences, Biochemistry, Chemistry +6

Subtilisin and α-chymotrypsin catalyzed synthesis of peptides containing arginine and lysine p-nitroanilides as c-terminal moieties

V. M. Stepanov, Elena Yu. Terent'eva, Tatiana L. Voyushina et al. · Bioorganic & Medicinal Chemistry · 1995 · 16 citations

Life Sciences, Biochemistry, Molecular Biology +11