Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

Autoimmune Disease, Lymphocyte Development, Adaptive Immune System +10

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.4K citations

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

Inflammation, Autoimmune Disease, Tissue Inflammation +11

Foxp3⁺CD25⁺CD4⁺ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

Shimon Sakaguchi, Masahiro Ono, Ruka Setoguchi et al. · Immunological Reviews · 2006 · 1.5K citations · Full text

Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice

Susumu Nakae, Aya Nambu, Katsuko Sudo et al. · The Journal of Immunology · 2003 · 1.3K citations · Full text