Chemical Communications · 1997 · 45 citations · 15 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsMacrocycle SynthesisRetrosynthetic AnalysisBiaryl FunctionalizationLactam MacrocyclesMacrocycle DiversificationMacrocycle Library SynthesisMacrocyclic CompoundsMacrocyclic Library ConstructionMacrolide AntibioticsStereoselective Macrocyclization
The effectiveness of the Suzuki coupling reaction in the formation of the AB biaryl moiety and the beneficial role of a preexisting COD ring system in a lactamization approach to the AB-COD ring system of vancomycin is demonstrated.
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Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine
George M. Sheldrick, Peter G. Jones, Olga Kennard et al. · Nature · 1978 · 291 citations
Patrick J. Loll, Anthony E. Bevivino, Brian D. Korty et al. · Journal of the American Chemical Society · 1997 · 137 citations