Patrick J. Loll

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

Daniel Picot, Patrick J. Loll, R. Michael Garavito · Nature · 1994 · 1.3K citations

X-ray Crystallography, Biochemistry, Natural Sciences +6

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

Patrick J. Loll, Daniel Picot, R. Michael Garavito · Nature Structural Biology · 1995 · 485 citations

Crystal Structure, Medicinal Chemistry, Biochemistry +10

Structural Analysis of NSAID Binding by Prostaglandin H₂ Synthase:  Time-Dependent and Time-Independent Inhibitors Elicit Identical Enzyme Conformations

Barry S. Selinsky, Kushol Gupta, Caroline T. Sharkey et al. · Biochemistry · 2001 · 280 citations

The crystal structure of the ternary complex of staphylococcal nuclease, Ca²⁺ and the inhibitor pdTp, refined at 1.65 Å

Patrick J. Loll, Eaton E. Lattman · Proteins Structure Function and Bioinformatics · 1989 · 262 citations

Synthesis and Use of Iodinated Nonsteroidal Antiinflammatory Drug Analogs as Crystallographic Probes of the Prostaglandin H₂ Synthase Cyclooxygenase Active Site^,

Patrick J. Loll, Daniel Picot, Opinya A. Ekabo et al. · Biochemistry · 1996 · 162 citations