P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks

Linda Schultz, Nabil Chehab, Asra Malikzay, +1

The Journal of Cell Biology

Dna DamageMolecular BiologyCell DeathNijmegen Breakage SyndromeCell Cycle +16

53BP1, a Mediator of the DNA Damage Checkpoint

Bin Wang, Shuhei Matsuoka, Phillip B. Carpenter, +1

Science

Dna Damage CheckpointChromatinGenome InstabilityTumor BiologyDna Damage +13

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

Nadya Dimitrova, Yi-Chun M. Chen, David L. Spector, +1

Nature

ChromatinGenome InstabilityChromatin StructureChromatin RemodelingNatural Sciences +9

Tumor Suppressor P53 Binding Protein 1 (53bp1) Is Involved in DNA Damage–Signaling Pathways

Irène Rappold, Kuniyoshi Iwabuchi, Takayasu Date, +1

The Journal of Cell Biology

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

Claudia Lukas, Jacob Falck, Jiřina Bártková, +2

Nature Cell Biology

ChromatinGenome InstabilityDna DamageCell RegulationChromatin Remodeling +8

p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice

Irene M. Ward, Kay Minn, Jan van Deursen, +1

Molecular and Cellular Biology

Tumor BiologyGenome InstabilityChromatinMedicineTumor Suppression +11

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

Richard A. DiTullio, Tamara A. Mochan, Monica Venere, +4

Nature Cell Biology

OncologyMedicineCell DeathCancer Cell BiologyHuman Cancer +8

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

Irene M. Ward, Kay Minn, Katherine G. Jorda, +1

Journal of Biological Chemistry

Phosphorylation and Rapid Relocalization of 53BP1 to Nuclear Foci upon DNA Damage

Lindsay Anderson, Catherine Henderson, Yasuhisa Adachi

Molecular and Cellular Biology

53BP1 facilitates long-range DNA end-joining during V(D)J recombination

Simone Difilippantonio, Eric J. Gapud, Nancy Wong, +9

Nature

Genome InstabilityJ RecombinationGeneticsMolecular BiologyMolecular Genetics +2