Concepedia

Replication Checkpoint Signaling

Replication Checkpoint Signaling is a regulatory mechanism in the DNA damage response pathway that specifically monitors replication fork progression and coordinates cell cycle arrest, replication origin firing suppression, and fork stabilization in response to replication stress.

563

Publications

55.5K

Citations

2.9K

Authors

703

Institutions

Publications per year

2017–2026

99

Parents

Publications

563

ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Hui Zhao, Helen Piwnica‐Worms · Molecular and Cellular Biology · 2001 · 1.1K citations · Full text

, , +17

Replication fork stability confers chemoresistance in BRCA-deficient cells

Arnab Ray Chaudhuri, Elsa Callén, Xia Ding et al. · Nature · 2016 · 932 citations · Full text

, , +14

Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint Defects

José M. Sogo, Massimo Lopes, Marco Foiani · Science · 2002 · 821 citations

, , +17

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

Tony Byun, Marcin Pacek, Muh‐Ching Yee et al. · Genes & Development · 2005 · 757 citations · Full text

, , +17

The DNA replication checkpoint response stabilizes stalled replication forks

Massimo Lopes, Cecilia Cotta‐Ramusino, Achille Pellicioli et al. · Nature · 2001 · 739 citations

, , +13

1–5 of 563

Authors

2.9K

  1. PR
    Paul Russell

    Scripps Research Institute, United States

    19 publications · 1.9K citations

    19

    h-index

  2. SJ
    Stephen J. Elledge

    Howard Hughes Medical Institute, United States

    12 publications · 3.4K citations

    12

    h-index

  3. HM
    Hisao Masai

    Tokyo Metropolitan Institute of Medical Science, Japan

    10 publications · 490 citations

    10

    h-index

  4. PP
    Philippe Pasero

    Institut de Génétique Humaine, France

    10 publications · 1.1K citations

    10

    h-index

  5. WG
    William G. Dunphy

    California Institute of Technology, United States

    10 publications · 1.5K citations

    10

    h-index

1–5 of 2.9K

Institutions

703

  1. Harvard University

    Cambridge, United States

    29 h-index

    88 publications

    12.3K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    63 publications

    15.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    134 publications

    10.6K citations

  4. Scripps Research Institute

    San Diego, United States

    24 h-index

    73 publications

    8K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    18 h-index

    77 publications

    6.4K citations

  6. Cancer Research UK

    London, United Kingdom

    18 h-index

    75 publications

    7.1K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    17 h-index

    89 publications

    15K citations

  8. University of Oxford

    Oxford, United Kingdom

    16 h-index

    44 publications

    4.6K citations

1–8 of 703

Venues

  1. Journal of Biological Chemistry

    JBC · 57 publications · 4.4K citations

    39

    h-index

  2. Molecular Cell

    37 publications · 5.7K citations

    33

    h-index

  3. Molecular and Cellular Biology

    MCB · 38 publications · 4.5K citations

    33

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 30 publications · 3.2K citations

    27

    h-index

  5. The EMBO Journal

    28 publications · 3.3K citations

    26

    h-index

1–5