Concepedia

Synthesis and evaluation of cis-3,4-disubstituted piperidines as potent CC chemokine receptor 2 (CCR2) antagonists

Robert J. Cherney, David J. Nelson, Yvonne C. Lo, Gengjie Yang, Peggy Scherle, Heather Jezak, Kimberly A. Solomon, Percy H. Carter, Carl P. Decicco

Bioorganic & Medicinal Chemistry Letters · 2008 · 24 citations · 11 references

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11

Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance

Nozomu Kamei, Kazuyuki Tobe, Ryo Suzuki et al. · Journal of Biological Chemistry · 2006 · 900 citations · Full text

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Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists

Tara Mirzadegan, Frank Diehl, Bettina Ebi et al. · Journal of Biological Chemistry · 2000 · 249 citations · Full text

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Monocyte Chemoattractant Protein-1 (CCL2) in Inflammatory Disease and Adaptive Immunity: Therapeutic Opportunities and Controversies

Christine Daly, BARRETT J. ROLLINS · Microcirculation · 2003 · 166 citations

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CCR2:  Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach

Theo A. Berkhout, Frank E. Blaney, Angela Bridges et al. · Journal of Medicinal Chemistry · 2003 · 95 citations · Full text

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The CCR2 receptor as a therapeutic target

Manuel Feria, Federico Díaz‐González · Expert Opinion on Therapeutic Patents · 2005 · 64 citations

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