Theo A. Berkhout - Concepedia

Concepedia

Author

Theo A. Berkhout

Also Known As

T A Berkhout, T Berkhout, T. A. Berkhout, T. Berkhout, T.A. Berkhout, Theo A Berkhout, Theo A. BERKHOUT, Theo A. Berkhout, Theo BERKHOUT, Theo Berkhout

34

Publications

2.3K

Citations

20

H-Index

82

Concepts

All Affiliations

New Frontier Molecular Discovery (United Kingdom)GlaxoSmithKline (United Kingdom)Utrecht University Christian-Albrechts-Universität zu Kiel

TA

About

Theo A. Berkhout is an author at New Frontier specializing in medicine, biochemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	19	1.4K
2	Biochemistry	14	16	1.2K
3	Natural Sciences	10	10	844
4	Health Sciences	2	2	213
5	Biology	1	1	12

Theo A. Berkhout

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25

Publications

2.3K

Citations

20

H-Index

	Year	Citations
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion Christian Hundhausen, Dominika Misztela, Theo A. Berkhout, Blood	2003	714
The Transmembrane CXC-Chemokine Ligand 16 Is Induced by IFN-γ and TNF-α and Shed by the Activity of the Disintegrin-Like Metalloproteinase ADAM10 Sören Abel, Christian Hundhausen, Rolf Mentlein, The Journal of Immunology ImmunologyMolecular BiologyImmunologic MechanismMurine Cxcl16Adam10-deficient Mice	2004	440
Fractalkine Is Expressed by Smooth Muscle Cells in Response to IFN-γ and TNF-α and Is Modulated by Metalloproteinase Activity Andreas Ludwig, Theo A. Berkhout, Kitty Moores, The Journal of Immunology ImmunologyCytoskeletonCellular PhysiologyInflammationAngiogenesis	2002	143
The role of ATP citrate-lyase in the metabolic regulation of plasma lipids John Yates, Theo A. Berkhout, Brian Jackson, Biochemical Journal Plasma LipidsPlasma CholesterolCholesterol SynthesisOxidative StressAtp Citrate-lyase	1998	136
The role of fractalkine in the recruitment of monocytes to the endothelium Gayle A. Chapman, Kitty Moores, Jayneeta Gohil, European Journal of Pharmacology InflammationCell PhysiologyGranulocyteCell SignalingPhysiology	2000	99
Cloning, in Vitro Expression, and Functional Characterization of a Novel Human CC Chemokine of the Monocyte Chemotactic Protein (MCP) Family (MCP-4) That Binds and Signals through the CC Chemokine Receptor 2B Theo A. Berkhout, Henry M. Sarau, Kitty Moores, Journal of Biological Chemistry	1997	97
CCR2: Characterization of the Antagonist Binding Site from a Combined Receptor Modeling/Mutagenesis Approach Theo A. Berkhout, Frank E. Blaney, Angela Bridges, Journal of Medicinal Chemistry Crystal StructureAntagonist Binding SiteDrug TargetMolecular BiologyNovel Antagonist Ligands	2003	95
The effect of (−)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2 Theo A. Berkhout, Louis M. Havekes, Neil Pearce, Biochemical Journal 3-Hydroxy-3-methylglutaryl-coa Reductase LevelsOxidative StressAtp Citrate-lyaseMetabolic SyndromeHepatotoxicity	1990	77
CCR2B receptor antagonists: conversion of a weak HTS hit to a potent lead compound Ian T. Forbes, David G. Cooper, Emma K. Dodds, Bioorganic & Medicinal Chemistry Letters Ccr2b Receptor AntagonistsBiochemistryFunctional SelectivityMedicineG Protein-coupled Receptor	2000	53
Preferential lipid association and mode of penetration of apocytochrome c in mixed model membranes as monitored by tryptophanyl fluorescence quenching using brominated phospholipids Theo A. Berkhout, Annie Rietveld, Ben de Kruijff Biochimica et Biophysica Acta (BBA) - Biomembranes Tryptophanyl FluorescenceLipid AnalysisApocytochrome CProteinlipid InteractionBiochemistry	1987	51

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