Concepedia

Myocardial Remodeling Is Controlled by Myocyte-Targeted Gene Regulation of Phosphodiesterase Type 5

Manling Zhang, Eiki Takimoto, Steven Hsu, Dong I. Lee, Takahiro Nagayama, Thomas Danner, Norimichi Koitabashi, Andreas S. Barth, Djahida Bedja, Kathleen L. Gabrielson,

Journal of the American College of Cardiology · 2010 · 83 citations · 22 references

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22

Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

Eiki Takimoto, Hunter C. Champion, Manxiang Li et al. · Nature Medicine · 2005 · 898 citations

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Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility

Jayan Nagendran, Stephen L. Archer, Daniel Soliman et al. · Circulation · 2007 · 528 citations · Full text

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Phosphodiesterase-5 Inhibition With Sildenafil Attenuates Cardiomyocyte Apoptosis and Left Ventricular Dysfunction in a Chronic Model of Doxorubicin Cardiotoxicity

Patrick W. Fisher, Fadi N. Salloum, Anindita Das et al. · Circulation · 2005 · 350 citations · Full text

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Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain Promoter

Atsushi Sanbe, James Gulick, Mark C. Hanks et al. · Circulation Research · 2003 · 250 citations

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cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism

Eiki Takimoto, Hunter C. Champion, Diego Belardi et al. · Circulation Research · 2004 · 215 citations · Full text

, , +17