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Identification of Cys385 in the isolated kinase insertion domain of heme-regulated eIF2α kinase (HRI) as the heme axial ligand by site-directed mutagenesis and spectral characterization

Signal TransductionMolecular BiologyHeme Axial LigandHeme SignalingSpectral CharacterizationHeme-regulated Eif2α KinaseHeme HomeostasisMedicineCell BiologyCell SignalingProtein PhosphorylationHeme Trafficking