Concepedia

Heme Regulation

Heme Regulation is a biochemical mechanism that controls the synthesis, degradation, and cellular homeostasis of heme through feedback modulation of key enzymes and transport proteins to maintain metabolic balance and prevent cytotoxic accumulation.

984

Publications

58.6K

Citations

4.1K

Authors

1K

Institutions

Publications per year

2017–2026

147

Parents

Publications

984

Isolation and Characterization of a cDNA from the Rat Brain that Encodes Hemoprotein Heme Oxygenase‐3

William K. McCoubrey, Tony Jun Huang, Mahin D. Maines · European Journal of Biochemistry · 1997 · 823 citations · Full text

, , +14

Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible.

M D Maines, G M Trakshel, R. Krishnan Kutty · Journal of Biological Chemistry · 1986 · 759 citations · Full text

, , +17

Rev-erbα, a Heme Sensor That Coordinates Metabolic and Circadian Pathways

Lei Yin, Nan Wu, Joshua C. Curtin et al. · Science · 2007 · 716 citations

, , +17

The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

Partha Krishnamurthy, Douglas D. Ross, Takeo Nakanishi et al. · Journal of Biological Chemistry · 2004 · 653 citations · Full text

, , +17

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

Leonard Guarente, Thomas L. Mason · Cell · 1983 · 643 citations

, , +14

1–5 of 984

Authors

4.1K

  1. KI
    Kazuhiko Igarashi

    Tohoku University, Japan

    24 publications · 2.4K citations

    19

    h-index

  2. SS
    Shigeki Shibahara

    Tohoku University, Japan

    19 publications · 1.6K citations

    18

    h-index

  3. NG
    Nader G. Abraham

    New York Medical College, United States

    19 publications · 1.1K citations

    17

    h-index

  4. SS
    Shigeru Sassa

    Rockefeller University, United States

    18 publications · 802 citations

    16

    h-index

  5. MY
    Masayuki Yamamoto

    Tohoku University, Japan

    16 publications · 1.3K citations

    15

    h-index

1–5 of 4.1K

Institutions

1K

  1. Massachusetts Institute of Technology

    Cambridge, United States

    30 h-index

    115 publications

    8.7K citations

  2. Tohoku University

    Sendai, Japan

    29 h-index

    188 publications

    13.9K citations

  3. New York Medical College

    Valhalla, United States

    18 h-index

    82 publications

    5.6K citations

  4. Rockefeller University

    New York, United States

    18 h-index

    61 publications

    3.5K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    52 publications

    2.2K citations

  6. Harvard University

    Cambridge, United States

    16 h-index

    70 publications

    9.1K citations

  7. University of Michigan

    Ann Arbor, United States

    16 h-index

    67 publications

    3.2K citations

  8. Harvard–MIT Division of Health Sciences and Technology

    Cambridge, United States

    14 h-index

    46 publications

    3.5K citations

1–8 of 1K

Venues

  1. Journal of Biological Chemistry

    JBC · 115 publications · 9.1K citations

    58

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 42 publications · 4.1K citations

    33

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 60 publications · 2.9K citations

    32

    h-index

  4. Blood

    28 publications · 2.5K citations

    25

    h-index

  5. Biochemistry

    29 publications · 1.8K citations

    24

    h-index

1–5