Kazuhiko Igarashi

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

Akira Kobayashi, Moon-Il Kang, Hiromi Okawa et al. · Molecular and Cellular Biology · 2004 · 2.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study.

Masato Tominaga, Hideyuki Eguchi, Hideo Manaka et al. · Diabetes Care · 1999 · 1.2K citations

Medicine, Endocrinology, Internal Medicine +13

A Third Recognition Element in Bacterial Promoters: DNA Binding by the α Subunit of RNA Polymerase

Wilma Ross, Khoosheh K. Gosink, Julia Salomon et al. · Science · 1993 · 799 citations

Life Sciences, Microbiology, Molecular Biology +17