Enhancing the aqueous solubility of d4T-based phosphoramidate prodrugs

Aromatic substituent constants for structure-activity correlations

Corwin Hansch, Albert J. Leo, Stefan Unger et al. · Journal of Medicinal Chemistry · 1973 · 1.3K citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Aryl Phosphoramidate Derivatives of d4T Have Improved Anti-HIV Efficacy in Tissue Culture and May Act by the Generation of a Novel Intracellular Metabolite

Christopher McGuigan, Dominique Cahard, Hendrika M. Sheeka et al. · Journal of Medicinal Chemistry · 1996 · 228 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT

Christopher McGuigan, Ranjith Pathirana, Jan Balzarini et al. · Journal of Medicinal Chemistry · 1993 · 215 citations

Pharmacy, Pharmaceutics, Pharmacology +8

Pro-Nucleotides - Recent Advances in the Design of Efficient Tools for the Delivery of Biologically Active Nucleoside Monophosphates

Chris Meier · Synlett · 1998 · 113 citations · Full text

Pharmacy, Biochemistry, Molecular Pharmaceutics +9

Characterization of the Activation Pathway of Phosphoramidate Triester Prodrugs of Stavudine and Zidovudine

Didier Saboulard, Lieve Naesens, Dominique Cahard et al. · Molecular Pharmacology · 1999 · 111 citations

Medicine, Medicinal Chemistry, Pharmacology +17