Hendrika M. Sheeka

Aryl Phosphoramidate Derivatives of d4T Have Improved Anti-HIV Efficacy in Tissue Culture and May Act by the Generation of a Novel Intracellular Metabolite

Christopher McGuigan, Dominique Cahard, Hendrika M. Sheeka et al. · Journal of Medicinal Chemistry · 1996 · 228 citations

Aryl Phosphoramidate Derivatives, Antiviral Drug, Phosphate Diester +19

Phosphoramidate derivatives of d4T with improved anti-HIV efficacy retain full activity in thymidine kinase-deficient cells

Christopher McGuigan, Dominique Cahard, Hendrika M. Sheeka et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 57 citations

Thymidine Kinase-deficient Cells, Medicinal Chemistry, Full Activity +7

Phosphate derivatives of d4T as inhibitors of HIV

Christopher McGuigan, Hendrika M. Sheeka, Naheed Mahmood et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 30 citations

Antiviral Compound, Medicine, Human Retrovirus +6

Certain phosphoramidate derivatives of dideoxy uridine (ddU) are active against HIV and successfully by‐pass thymidine kinase

Christopher McGuigan, Patrice Bellevergue, Hendrika M. Sheeka et al. · FEBS Letters · 1994 · 18 citations · Full text

Masked Phosphates, Bioorganic Chemistry, Molecular Biology +17