Nucleosides and Nucleotides · 1997 · 13 citations · 13 references
PharmacyBiochemistryMolecular BiologyEnzymologyNucleic Acid BiochemistryNucleic Acid ChemistryDna ChemistryModified Nucleic AcidsNucleic Acid ModificationNucleic Acid SynthesisNucleobase ChemistryOligonucleotide ChemistryChemical Modification Of OligonucleotidesEnzyme Conformational StabilityOligonucleotide HybridizationOligonucleotide Synthesis
Abstract 3′-C-Aminomethyl- and 3′-C-methylthymidine were synthesized and incorporated into oligodeoxynucleotides. Hybridization and enzyme stability of the modified oligonucleotides containing the 3′-C-branched thymidines are discussed.
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