Concepedia

Modified Nucleic Acids

Modified Nucleic Acids is a class of nucleic acid derivatives in which the inherent chemical structure of natural nucleic acids is altered through the substitution or addition of non-native functional groups, thereby endowing them with enhanced or novel physicochemical and biological properties.

1.3K

Publications

60.8K

Citations

3.9K

Authors

910

Institutions

Publications per year

2017–2026

122

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Publications

1.3K

Preparation of transforming deoxyribonucleic acid by phenol treatment

Hiuga Saito, Kin‐ichiro Miura · Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects · 1963 · 1.8K citations

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The RNA modification database, RNAMDB: 2011 update

William A. Cantara, P. F. Crain, Jef Rozenski et al. · Nucleic Acids Research · 2010 · 824 citations · Full text

, , +9

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

Sandra Freier · Nucleic Acids Research · 1997 · 684 citations · Full text

, , +17

5-Hydroxymethylcytosine is a predominantly stable DNA modification

Martin Bachman, Santiago Uribe‐Lewis, Xiaoping Yang et al. · Nature Chemistry · 2014 · 600 citations

, , +11

Chemical specificity of nucleic acids and mechanism of their enzymatic degradation

Erwin Chargaff · Cellular and Molecular Life Sciences · 1950 · 511 citations

, , +16

1–5 of 1.3K

Authors

3.9K

  1. JW
    Jesper Wengel

    University of Southern Denmark, Denmark

    30 publications · 1.1K citations

    19

    h-index

  2. SO
    Satoshi Obika

    The University of Osaka, Japan

    27 publications · 936 citations

    17

    h-index

  3. TI
    Takeshi Imanishi

    The University of Osaka, Japan

    17 publications · 974 citations

    15

    h-index

  4. MJ
    Morris J. Robins

    Brigham Young University, United States

    14 publications · 532 citations

    13

    h-index

  5. PH
    Piet Herdewijn

    Rega Institute for Medical Research, Belgium

    13 publications · 692 citations

    12

    h-index

1–5 of 3.9K

Institutions

910

  1. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    111 publications

    4.4K citations

  2. University of Southern Denmark

    Odense, Denmark

    23 h-index

    96 publications

    3.9K citations

  3. The University of Tokyo

    Tokyo, Japan

    22 h-index

    92 publications

    8K citations

  4. The University of Osaka

    Osaka, Japan

    20 h-index

    162 publications

    5.7K citations

  5. Ionis Pharmaceuticals (United States)

    Carlsbad, United States

    19 h-index

    108 publications

    7.1K citations

  6. Vanderbilt University

    Nashville, United States

    15 h-index

    42 publications

    1.6K citations

  7. Institute of Bioorganic Chemistry

    Moscow, Russia

    15 h-index

    50 publications

    1.4K citations

  8. Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

    Prague, Czechia

    14 h-index

    53 publications

    1.9K citations

1–8 of 910

Venues

  1. Nucleic Acids Research

    98 publications · 6.9K citations

    43

    h-index

  2. Biochemistry

    44 publications · 2.3K citations

    30

    h-index

  3. Journal of the American Chemical Society

    JACS · 34 publications · 2.1K citations

    27

    h-index

  4. Tetrahedron Letters

    65 publications · 1.9K citations

    26

    h-index

  5. The Journal of Organic Chemistry

    JOC · 43 publications · 1.5K citations

    23

    h-index

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