Human heat shock protein 70 (Hsp70) as a peripheral membrane protein

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

Monica Bucciantini, Elisa Giannoni, Fabrizio Chiti et al. · Nature · 2002 · 2.4K citations

Life Sciences, Biochemistry, Molecular Biology +17

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

Life Sciences, Genetics, Neurology +17

Small-volume extrusion apparatus for preparation of large, unilamellar vesicles

Robert C. MacDonald, Robert C. MacDonald, Ruby I. MacDonald et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 1.5K citations

Life Sciences, Biochemistry, Intracellular Transport +9

Chaperone Suppression of α-Synuclein Toxicity in a <i>Drosophila</i> Model for Parkinson's Disease

Pavan K. Auluck, Ho Yin Edwin Chan, John Q. Trojanowski et al. · Science · 2002 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Principles of Fluorescence Spectroscopy

Mahendra Kumar Jain · Journal of Biochemical and Biophysical Methods · 1984 · 1K citations

Natural Sciences, Biophysics, Physics +12