Concepedia

Adenosine is required for sustained inflammasome activation via the A2A receptor and the HIF-1α pathway

Xinshou Ouyang, Ayaz Ghani, Ahsan Malik, Tuere Wilder, Oscar R. Colegio, Richard A. Flavell, Bruce N. Cronstein, Wajahat Z. Mehal

Nature Communications · 2013 · 125 citations · 24 references

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24

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Franz Bauernfeind, Gábor Horváth, Andrea Stutz et al. · The Journal of Immunology · 2009 · 2.9K citations · Full text

, , +17

Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation

Cheng‐Jun Hu, Li-Yi Wang, Lewis A. Chodosh et al. · Molecular and Cellular Biology · 2003 · 1.4K citations · Full text

, , +15

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

Akio Ohta, Michail V. Sitkovsky · Nature · 2001 · 1.3K citations

, , +14

Purinergic Signaling during Inflammation

Holger K. Eltzschig, Michail V. Sitkovsky, Simon C. Robson · New England Journal of Medicine · 2012 · 698 citations

, , +14

Cutting Edge: TNF-α Mediates Sensitization to ATP and Silica via the NLRP3 Inflammasome in the Absence of Microbial Stimulation

Luigi Franchi, Tatjana Eigenbrod, Gabriel Núñez · The Journal of Immunology · 2009 · 566 citations · Full text

, , +17