Bruce N. Cronstein

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.

Bruce N. Cronstein, Steven C. Kimmel, Richard I. Levin et al. · Proceedings of the National Academy of Sciences · 1992 · 729 citations · Full text

Endothelial Cells, Immune Regulation, Immunology +21

The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

Bruce N. Cronstein, Dwight Naime, Edward Ostad · Journal of Clinical Investigation · 1993 · 673 citations · Full text

Inflammation, Molecular Pharmacology, Local Adenosine Release +15

Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.

Bruce N. Cronstein, Sara B. Kramer, Gerald Weissmann et al. · The Journal of Experimental Medicine · 1983 · 468 citations · Full text

Adenosine Metabolism, Redox Biology, Cellular Physiology +17

Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells.

Bruce N. Cronstein, Richard I. Levin, Joseph K. Belanoff et al. · Journal of Clinical Investigation · 1986 · 418 citations · Full text

Inflammation, Endothelial Cell Pathobiology, Medicinal Chemistry +15

The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively.

Bruce N. Cronstein, L Daguma, D Nichols et al. · Journal of Clinical Investigation · 1990 · 377 citations · Full text

Adenosine Receptors, Immunology, Distinct Adenosine Receptors +22