Lac operator repeats generate a traceable fragile site in mammalian cells

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

Chromatin, Tumor Biology, Genome Instability +11

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

Dna Damage Checkpoint, Genome Instability, Dna Damage +11

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer et al. · Cell · 2009 · 980 citations · Full text

Chromatin, Genome Instability, Efficient Replication +11

In vivo dynamics of RNA polymerase II transcription

Xavier Darzacq, Yaron Shav‐Tal, Valeria de Turris et al. · Nature Structural & Molecular Biology · 2007 · 677 citations · Full text

Transcriptional Regulation, Natural Sciences, Rna Biology +6

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

Kok‐Lung Chan, Timea Palmai‐Pallag, Songmin Ying et al. · Nature Cell Biology · 2009 · 600 citations

Chromatin, Genome Instability, Cell Division +12