Concepedia

A Homogeneous High Throughput Nonradioactive Method for Measurement of Functional Activity of Gs-Coupled Receptors in Membranes

Michael Allen, David A. Hall, Barbara W. Collins, Keith M. Moore

SLAS DISCOVERY · 2002 · 16 citations · 13 references

DOIFull text

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Concepts

References

13

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

, , +16

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

Earl W. Sutherland, Theodore W. Rall · Journal of Biological Chemistry · 1958 · 1.1K citations · Full text

, , +12

Pharmacologic Analysis of Drug Receptor Interaction

Kenakin. T. Kenakin · Therapeutic Drug Monitoring · 1988 · 930 citations

, , +17

CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding

Stephane Litschig, F. Gasparini, D Rueegg et al. · Molecular Pharmacology · 1999 · 343 citations

, , +16