Concepedia

Publication | Closed Access

Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in <scp>D</scp>own syndrome mouse models and in humans

DOI

270

Citations

32

References

2013

Year

Rafael de la Torre, Susana Solá, Meritxell Pons‐Espinal, Arnaud Duchon, María Martínez de Lagrán, Montserrat Fitó, Bessy Benejam, Klaus Langohr, Joan Rodríguez, Mitona Pujadas,
Molecular Nutrition & Food Research

Abstract

We conclude that EGCG is a promising therapeutic tool for cognitive enhancement in DS, and its efficacy may depend of Dyrk1A inhibition.

References

YearCitations

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