The Dominant Role of the Prosegment of Prorenin in Determining the Rate of Activation by Acid or Trypsin: Studies with Molecular Chimeras

Cloning and sequence analysis of cDNA for human renin precursor.

T Imai, Hitoshi Miyazaki, Shinichi Hirose et al. · Proceedings of the National Academy of Sciences · 1983 · 271 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Isolation and characterization of native human renin derived from Chinese hamster ovary cells

Roger A. Poorman, Daniel P. Palermo, Leonard Post et al. · Proteins Structure Function and Bioinformatics · 1986 · 92 citations

Life Sciences, Biochemistry, Molecular Biology +13

Structure of the rat renin gene

Akiyoshi Fukamizu, Kazuto Nishi, Takeshi Cho et al. · Journal of Molecular Biology · 1988 · 86 citations

Life Sciences, Genetics, Molecular Genetics +9

Two-step prorenin-renin conversion. Isolation of an intermediary form of activated prorenin.

F. H. M. Derkx, MADH Schalekamp, Maarten A.D.H. Schalekamp · Journal of Biological Chemistry · 1987 · 77 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Nonproteolytic “activation” of prorenin by active site-directed renin inhibitors as demonstrated by renin-specific monoclonal antibody

F. H. M. Derkx, Jaap Deinum, M Lipovski et al. · Journal of Biological Chemistry · 1992 · 64 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17