Concepedia

β-Aminoketones as prodrugs with pH-controlled activation

Ana Luı́sa Simplı́cio, John M. Clancy, John F. Gilmer

International Journal of Pharmaceutics · 2006 · 33 citations · 9 references

DOI

Concepts

References

9

Design, Synthesis, and Biological Evaluation of Doxorubicin−Formaldehyde Conjugates Targeted to Breast Cancer Cells

Patrick Burke, Tad H. Koch · Journal of Medicinal Chemistry · 2004 · 54 citations · Full text

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A Novel Method for Michael Addition and Epoxidation of Chalcones in a Water Suspension Medium: A Completely Organic Solvent-Free Synthetic Procedure

F. Toda, Hideaki Takumi, Masuhiro Nagami et al. · Heterocycles · 1998 · 31 citations · Full text

, , +4

Effects of Mannich bases on cellular glutathione and related enzymes of Jurkat cells in culture conditions

Mustafa Gül, Halise İnci Gül, Otto Hänninen · Toxicology in Vitro · 2002 · 29 citations

, , +13

Evaluation of Some Mannich Bases Derived from Substituted Acetophenones Against P-388 Lymphocytic Leukemia and on Respiration in Isolated Rat Liver Mitochondria

J.R. Dimmock, Karuppiah Prakash Shyam, Nadège Hamon et al. · Journal of Pharmaceutical Sciences · 1983 · 19 citations

, , +11

Kinetic approach to the development in .BETA.-lactam antibiotics. II. Prodrug. I. Simultaneous determination of hetacillin and ampicillin, and its application to the stability of hetacillin in aqueous solution.

Akira Tsuji, Tsukinaka Yamana · Chemical and Pharmaceutical Bulletin · 1974 · 17 citations · Full text

, , +16