A Novel Method for Michael Addition and Epoxidation of Chalcones in a Water Suspension Medium: A Completely Organic Solvent-Free Synthetic Procedure

Abstract

Very efficient Michael addition reactions of amines, thiophenol and methyl acetylacetate to chalcone, and epoxidation of chalcone derivatives with NaOCI, in a water suspension medium have been developed as completely organic solvent-free reactions.