Concepedia

Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo

Dimitris P. Xirodimas, Mark K. Saville, Charlotte E. Edling, David P. Lane

Oncogene · 2001 · 167 citations · 34 references

DOI

Concepts

References

34

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

Reiko Honda, Hirofumi Tanaka, Hideyo Yasuda · FEBS Letters · 1997 · 1.9K citations

, , +14

Recognition of the polyubiquitin proteolytic signal

Julia S. Thrower, Laura Hoffman, Martin Rechsteiner et al. · The EMBO Journal · 2000 · 1.7K citations · Full text

, , +6

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

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