Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against ischemia-reperfusion injury in rat hearts

Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow.

Giuseppe Ambrosio, Jay L. Zweíer, Carlo Duilio et al. · Journal of Biological Chemistry · 1993 · 520 citations · Full text

Life Sciences, Cardiology, Physiology +17

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

Andrew P. Halestrap, CP Connern, Elinor J. Griffiths et al. · 1997 · 420 citations

Life Sciences, Cardiology, Pharmacology +17

Cyclosporin A binding in mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

Andrew P. Halestrap, Cathal P. Connern, Elinor J. Griffiths et al. · Molecular and Cellular Biochemistry · 1997 · 348 citations

Life Sciences, Cardiology, Pharmacology +17

Morphological and Molecular Characterization of Adult Cardiomyocyte Apoptosis During Hypoxia and Reoxygenation

Peter M. Kang, Armin Haunstetter, Hiroki Aoki et al. · Circulation Research · 2000 · 319 citations · Full text

Life Sciences, Cardiology, Cell Biology +15

The Thiol-specific Antioxidant Enzyme Prevents Mitochondrial Permeability Transition

Alicia J. Kowaltowski, Luís Eduardo Soares Netto, Anı́bal E. Vercesi · Journal of Biological Chemistry · 1998 · 176 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17