Concepedia

Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy

Stacey L. Demento, Stephanie C. Eisenbarth, Harald G. Foellmer, Craig D. Platt, Michael J. Caplan, W. Mark Saltzman, Ira Mellman, Michel Ledizet, Erol Fikrig, Richard A. Flavell,

Vaccine · 2009 · 290 citations · 26 references

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References

26

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

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Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Catherine Dostert, Virginie Pétrilli, Robin van Bruggen et al. · Science · 2008 · 2.7K citations · Full text

, , +17

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

Stephanie C. Eisenbarth, Oscar R. Colegio, William O’Connor et al. · Nature · 2008 · 1.5K citations · Full text

, , +14

Regulation of Phagosome Maturation by Signals from Toll-Like Receptors

J. Magarian Blander, Ruslan Medzhitov · Science · 2004 · 990 citations

, , +17

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

Magdalena Kovacsovics-Bankowski, Kenneth L. Rock · Science · 1995 · 872 citations

, , +17